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A multidimensional workflow profiling of allogeneic virus-specific T cell therapies reveals potency-linked signatures

Abstract Allogeneic virus-specific T cell (VST) therapies offer distinct advantages, including scalability, rapid deployment, and manufacturing consistency, and have demonstrated efficacy in multiple clinical trials. However, identifying VST products with high therapeutic potential remains a major h...

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Hauptverfasser: Corey Smith, Vijayendra Dasari, Sriganesh Srihari, Laetitia Le Texier, Matthew Solomon, Archana Panikkar, Thuy Le, George Ambalathingal, Jyothy Raju, Sweera Rehan, Leone Beagley, Pauline Crooks, Panteha Khaledi, Arushi Mahajan, Pamela Mukhopadhyay, Rajiv Khanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2026-01-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-025-67924-w
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