Structure–Activity Relationship Studies Based on Quinazoline Derivatives as EGFR Kinase Inhibitors (2017–Present)

The epidermal growth factor receptor (EGFR) plays a critical role in the tumorigenesis of various forms of cancer. Targeting the mutant forms of EGFR has been identified as an attractive therapeutic approach and led to the approval of three generations of inhibitors. The quinazoline core has emerged...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Alexandru Șandor, Ioana Ionuț, Gabriel Marc, Ilioara Oniga, Dan Eniu, Ovidiu Oniga
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2023-04-01
Цуврал:	Pharmaceuticals
Нөхцлүүд:	quinazoline EGFR structure–activity relationship 4-anilino-quinazoline competitive inhibitor covalent inhibitor
Онлайн хандалт:	https://www.mdpi.com/1424-8247/16/4/534
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!