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Therapeutic efficacy of rifalazil (KRM-1648) in a M. ulcerans-induced Buruli ulcer mouse model.

Buruli ulcer (BU) is a skin disease caused by Mycobacterium ulcerans infection that requires long-term antibiotic treatment and/or surgical excision. In this study, we investigated the therapeutic efficacy of the rifamycin derivative, rifalazil (RLZ) (also known as KRM-1648), in an advanced M. ulcer...

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Principais autores: Hanako Fukano, Kazue Nakanaga, Masamichi Goto, Mitsunori Yoshida, Norihisa Ishii, Yoshihiko Hoshino
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2022-01-01
סדרה:PLoS ONE
גישה מקוונת:https://doi.org/10.1371/journal.pone.0274742
תגים: הוספת תג
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