Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt

Two related multisubunit tethering complexes promote endolysosomal trafficking in all eukaryotes: Rab5-binding CORVET that was suggested to transform into Rab7-binding HOPS. We have previously identified miniCORVET, containing Drosophila Vps8 and three shared core proteins, which are required for en...

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Autores principales:	Péter Lőrincz, Lili Anna Kenéz, Sarolta Tóth, Viktória Kiss, Ágnes Varga, Tamás Csizmadia, Zsófia Simon-Vecsei, Gábor Juhász
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2019-06-01
Colección:	eLife
Materias:	HOPS CORVET autophagy endocytosis crinophagy tethering
Acceso en línea:	https://elifesciences.org/articles/45631
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