Improving RNA-Seq precision with MapAl

With currently available RNA-Seq pipelines, expression estimates for most genes are very noisy. We here introduce MapAl, a tool for RNA-Seq expression profiling that builds on the established programs Bowtie and Cufflinks. In the post-processing of RNA-Seq reads, it incorporates gene models already a...

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Principais autores:	Paweł P Łabaj, Bryan E Linggi, H Steven eWiley, David P Kreil
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2012-04-01
叢編:	Frontiers in Genetics
主題:	Gene Expression Profiling RNA-Seq Reliability Transcriptomics measurement precision read mapping
在線閱讀:	http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00028/full
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