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Propolis mitigates busulfan-induced testicular dysfunction in rats: insights into redox stabilization, PCNA modulation, and caspase-3 inhibition

IntroductionTesticular cytofunctional defects are among the most hazardous effects of cancer chemotherapies. Propolis mitigates the fertility problems associated with gonadotoxic agents through its redox stabilizing, anti-apoptotic, and cytoprotective properties due to presence of bioactive agents i...

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Principais autores: Elham A. AbdAllah, Basant A. Eid, Hassan A. Hussein, Nasser S. Abou khalil, Sohair M. M. Ragab, Asmaa Y. Wahman, Hailah M. Almohaimeed, Rehab H. Moneeb, Hanem S. Abdel-Tawab, Zuhair M. Mohammedsaleh, Jameel Barnawi, Hanan S. A. Waly
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-10-01
Serier:Frontiers in Pharmacology
Fag:
propolis
busulfan
testis
histopathology
antioxidants
apoptosis
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2025.1656541/full
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