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Human-length Telomeres Limit Regeneration of Liver Epithelial Cells in MiceSummary

Background & Aims: Telomeres, or the ends of linear chromosomes, are critical for maintaining genomic integrity. The commonly used C57BL/6 mouse strain has telomeres about 5 times longer than those present in humans. We recently engineered the C57BL/6 “Telomouse” to enable the study of human len...

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Bibliografische gegevens
Hoofdauteurs: Michael Y. Hu, Melissa Rowe, Mark Tigue, Yitzhak Reizel, Riham Smoom, Yehuda Tzfati, Klaus H. Kaestner
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2026-01-01
Reeks:Cellular and Molecular Gastroenterology and Hepatology
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Online toegang:http://www.sciencedirect.com/science/article/pii/S2352345X25001961
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