USP10 Targeted Self-Deliverable siRNA to Prevent Scarring in the Cornea

Ocular scarring after surgery, trauma, or infection leads to vision loss. The transparent cornea is an excellent model system to test anti-scarring therapies. Cholesterol-conjugated fully modified asymmetric small interfering RNAs (siRNAs) (self-deliverable siRNAs [sdRNAs]) are a novel modality for...

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Bibliografiske detaljer

Principais autores:	Edward F. Boumil, Nileyma Castro, Andrew T. Phillips, Jon E. Chatterton, Sean M. McCauley, Alexey D. Wolfson, Taisia Shmushkovich, Marc Ridilla, Audrey M. Bernstein
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2020-09-01
Serier:	Molecular Therapy: Nucleic Acids
Fag:	myofibroblast integrin fibrosis scarring wound healing cornea
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2162253120302213
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