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The Fibrotic Phenotype of Human Precision-Cut Lung Slices Is Maintained after Cryopreservation

Human precision-cut lung slices (hPCLS) prepared from fibrotic lungs recapitulate the pathophysiological hallmarks of fibrosis. These hallmark features can also be induced by treating non-fibrotic hPCLS with a fibrotic cocktail (FC). As a result, the fibrotic and fibrosis-induced hPCLS are rapidly e...

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Principais autores: Méry Marimoutou, Vivek Patel, Jae Hun Kim, Niccole Schaible, Jose Alvarez, Joseph Hughes, McKenzie Obermok, Carlos Iván Rodríguez, Thomas Kallarakal, Béla Suki, Khalid Amin, Ramaswamy Krishnan, Holger Peter Behrsing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-08-01
coleção:Toxics
Assuntos:
fibrosis
cryopreservation
PCLS
IPF
human
stiffness
Acesso em linha:https://www.mdpi.com/2305-6304/12/9/637
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