A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells
Chimeric antigen receptor (CAR) development involves extensive empirical characterization of antigen-binding domain (ABD)/CAR constructs for clinical suitability. Here, we present a cost-efficient and rapid method for evaluating CARs in human Jurkat T cells. Using a modular CAR plasmid, a highly eff...
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| Автори: | , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2020-03-01
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| Серія: | Molecular Therapy: Methods & Clinical Development |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S2329050120300231 |
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