Dual mechanisms of a purified root extract of Paeonia lactiflora Pall. in regulating uric acid homeostasis: inhibition of hepatic synthesis and promotion of renal excretion in hyperuricemic rat models
IntroductionHyperuricemia (HUA), characterized by persistently elevated serum uric acid (UA), represents a growing global public-health concern. Current urate-lowering medications are often associated with hepatotoxicity and nephrotoxicity, highlighting the urgent need for safer, food-derived altern...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2026-04-01
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| Reeks: | Frontiers in Pharmacology |
| Onderwerpen: | |
| Online toegang: | https://www.frontiersin.org/articles/10.3389/fphar.2026.1800063/full |
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