Multiomics analysis demonstrated that TOPBP1 interacting checkpoint and Replication Regulator may serve as an immune-related biomarker indicative of poor prognosis in lung adenocarcinoma

BackgroundLung adenocarcinoma (LUAD) persists as a leading contributor to global cancer-associated mortality. Identifying key oncogenic drivers is crucial for improving therapeutic strategies. This study aimed to investigate the role of TICRR in LUAD progression and its potential as a therapeutic ta...

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Príomhchruthaitheoirí:	Chengbin Lin, Ziyi Chen, Wenbin Song, Long He, Hongyan Yu, Gaofeng Liang, Keyun Zhu, Jinxian He, Cangchang Shi
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2025-12-01
Sraith:	Frontiers in Immunology
Ábhair:	TICRR lung adenocarcinoma proliferation invasion immune evasion therapeutic target
Rochtain ar líne:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1740279/full
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