Cisplatin - induced peripheral neuropathy and biomarkers of gut microbial translocation in testicular germ cell tumor survivors

BackgroundCisplatin-induced peripheral neuropathy (CIPN) is a frequent and often persistent complication in survivors of testicular germ cell tumors (GCT) treated with curative therapy. Although several mechanisms have been proposed, the biological drivers of long-term neurotoxicity remain incomplet...

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Principais autores:	Dominika Rychtarikova, Katarina Kalavska, Jana Obertova, Patrik Palacka, Katarina Rejlekova, Zuzana Sycova-Mila, Zuzana Orszaghova, Peter Lesko, Rateb Alzeer, Lucia Vasilkova, Daniela Svetlovska, Beata Mladosievicova, Michal Pastorek, Matej Rychtarik, Barbora Vlkova, Peter Celec, Michal Mego, Michal Chovanec
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-05-01
Series:	Frontiers in Immunology
Assuntos:	biomarker cancer survivors cancer treatment cisplatin induced peripheral neuropathy gut microbial translocation late toxicity
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1827640/full
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