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Identification of potential biological targets of oxindole scaffolds via in silico repositioning strategies [version 1; peer review: 2 approved]

Background: Drug repurposing is an alternative strategy to traditional drug discovery that aims at predicting new uses for already existing drugs or clinical candidates. Drug repurposing has many advantages over traditional drug development, such as reduced attrition rates, time and costs. This is e...

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Hauptverfasser: Luca Pinzi, Guido Gambacorta, Annachiara Tinivella, Giulio Rastelli, Ian Baxendale
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000 Research Ltd 2022-02-01
Schriftenreihe:F1000Research
Schlagworte:
drug repurposing
ligand-based
molecular docking
data mining
synthetic products
eng
Online-Zugang:https://f1000research.com/articles/11-217/v1
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