The IRE1α-XBP1 Signaling Axis Promotes Glycolytic Reprogramming in Response to Inflammatory Stimuli

ABSTRACT Immune cells must be able to adjust their metabolic programs to effectively carry out their effector functions. Here, we show that the endoplasmic reticulum (ER) stress sensor Inositol-requiring enzyme 1 alpha (IRE1α) and its downstream transcription factor X box binding protein 1 (XBP1) en...

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Principais autores:	Bevin C. English, Hannah P. Savage, Scott P. Mahan, Vladimir E. Diaz-Ochoa, Briana M. Young, Basel H. Abuaita, Gautam Sule, Jason S. Knight, Mary X. O’Riordan, Andreas J. Bäumler, Renée M. Tsolis
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology 2023-02-01
叢編:	mBio
主題:	Brucella endoplasmic reticulum immunometabolism innate immunity
在線閱讀:	https://journals.asm.org/doi/10.1128/mbio.03068-22
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