Conducting a bayesian multi-armed trial with response adaptive randomization for comparative effectiveness of medications for CSPN

Background: Response adaptive randomization is popular in adaptive trial designs, but the literature detailing its execution is lacking. These designs are desirable for patients/stakeholders, particularly in comparative effectiveness research, due to the potential benefits including improving partic...

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Hlavní autoři:	Alexandra R. Brown, Byron J. Gajewski, Dinesh Pal Mudaranthakam, Mamatha Pasnoor, Mazen M. Dimachkie, Omar Jawdat, Laura Herbelin, Matthew S. Mayo, Richard J. Barohn
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-12-01
Edice:	Contemporary Clinical Trials Communications
Témata:	Conducting adaptive design Interim analyses Bayesian methods Outcome driven
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2451865423001667
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