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YTHDC2 inhibits rat bone mesenchymal stem cells osteogenic differentiation by accelerating RUNX2 mRNA degradation via m6A methylation

As the most abundant internal mRNA modification, N6-methyladenosine (m6A) RNA methylation has been found to influence many biological events including bone mesenchymal stem cells (BMSCs) osteogenic differentiation. YTH N6-methyladenosine RNA binding protein C2 （YTHDC2） is an m6A reading protein with...

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Principais autores: Bo Ma, Pei Cao, Lichen Zhang, Hongyi Zhu, Xuwen Ye, Lingjun Wang, Liang Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-08-01
coleção:Heliyon
Assuntos:
BMSCs
Osteogenic differentiation
m6A
YTHDC2
RUNX2
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S240584402306084X
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