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Using NGS to Uncover the Corruption of a Peptide Phage Display Selection

Phage display has been widely used to identify peptides binding to a variety of biological targets. In the current work, we planned to select novel peptides targeting CD4 through screening of a commercial phage display library (New England Biolabs Ph.D.<sup>TM</sup>-7). After three rounds of biopann...

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Principais autores: Danna Kamstrup Sell, Babak Bakhshinejad, Anders Wilgaard Sinkjaer, Ida Melissa Dawoodi, Mette Neiegaard Wiinholt, Ane Beth Sloth, Camilla Stavnsbjerg, Andreas Kjaer
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-09-01
Colecção:Current Issues in Molecular Biology
Assuntos:
biopanning
combinatorial diversity
corruption
fast-propagating clone
NGS
peptide library
Acesso em linha:https://www.mdpi.com/1467-3045/46/9/627
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