Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in Toxoplasma gondii

Toxoplasma gondii is a common zoonotic protozoan pathogen adapted to intracellular parasitism in many host cells of diverse organisms. Our previous work has identified 18 cyclic nucleotide phosphodiesterase (PDE) proteins encoded by the parasite genome, of which 11 are expressed during the lytic cyc...

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Autors principals:	Kim Chi Vo, Liberta Ruga, Olympia Ekaterini Psathaki, Rico Franzkoch, Ute Distler, Stefan Tenzer, Michael Hensel, Peter Hegemann, Nishith Gupta
Format:	Artigo
Idioma:	Inglês
Publicat:	American Association for the Advancement of Science (AAAS) 2022-01-01
Col·lecció:	Computational and Structural Biotechnology Journal
Matèries:	Apicomplexa Phosphodiesterase cAMP & cGMP signaling Lytic cycle Tachyzoite
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2001037022004275
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