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Top-down and bottom-up propagation of disease in the neuronal ceroid lipofuscinoses

BackgroundThe Neuronal Ceroid Lipofuscinoses (NCLs) may be considered distinct neurodegenerative disorders with separate underlying molecular causes resulting from monogenetic mutations. An alternative hypothesis is to consider the NCLs as related diseases that share lipofuscin pathobiology as the c...

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Bibliografiset tiedot
Päätekijät: John R. Ostergaard, Hemanth R. Nelvagal, Jonathan D. Cooper
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2022-11-01
Sarja:Frontiers in Neurology
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Linkit:https://www.frontiersin.org/articles/10.3389/fneur.2022.1061363/full
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