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Alterations in chromosome 1q in multiple myeloma randomized clinical trials: a systematic review

Abstract Extra copies of chromosome 1q21 (+1q: gain = 3 copies, amp >= 4 copies) are associated with worse outcomes in multiple myeloma (MM). This systematic review assesses the current reporting trends of +1q, the efficacy of existing regimens on +1q, and its prognostic implications in MM randomize...

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Huvudupphov: Karun Neupane, Gliceida Galarza Fortuna, Riyasha Dahal, Timothy Schmidt, Rafael Fonseca, Rajshekhar Chakraborty, Kelly Ann Koehn, Meera Mohan, Hira Mian, Luciano J. Costa, Douglas Sborov, Ghulam Rehman Mohyuddin
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Publishing Group 2024-01-01
Serie:Blood Cancer Journal
Länkar:https://doi.org/10.1038/s41408-024-00985-0
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