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Molecular Cloning and Functional Analysis of Gene Clusters for the Biosynthesis of Indole-Diterpenes in Penicillium crustosum and P. janthinellum

The penitremane and janthitremane families of indole-diterpenes are abundant natural products synthesized by Penicillium crustosum and P. janthinellum. Using a combination of PCR, cosmid library screening, and Illumina sequencing we have identified gene clusters encoding enzymes for the synthesis of...

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Autors principals: Matthew J. Nicholson, Carla J. Eaton, Cornelia Stärkel, Brian A. Tapper, Murray P. Cox, Barry Scott
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2015-07-01
Col·lecció:Toxins
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Accés en línia:http://www.mdpi.com/2072-6651/7/8/2701
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