Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition – implications for the next generation of DC vaccines

Current treatments for glioblastoma (GBM) have limited efficacy and significant morbidity and therefore new strategies are urgently needed. Dendritic cells have the power to create anti-tumor immune responses. The greater potency of circulating dendritic cells (DC) over laboratory-generated monocyte...

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Bibliografische Detailangaben

Hauptverfasser:	Jason Adhikaree, Hester Ann Franks, Constantinos Televantos, Poonam Vaghela, Aanchal Preet Kaur, David Walker, Marc Schmitz, Andrew Mark Jackson, Poulam Manubhai Patel
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2019-07-01
Schriftenreihe:	OncoImmunology
Schlagworte:	glioblastoma dendritic cell signalling immunotherapy mitogen activated protein kinase
Online-Zugang:	http://dx.doi.org/10.1080/2162402X.2019.1593803
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