Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Abstract The concept of trained immunity has redefined the understanding of innate immune memory and opened new opportunities for vaccine design. Polysaccharides, as naturally occurring pathogen‐associated molecular patterns (PAMPs), can activate pattern recognition receptors (PRRs) and induce durab...

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Autors principals:	Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-12-01
Col·lecció:	Advanced Science
Matèries:	immune engineering immunoadjuvant PAMP‐PRR polysaccharide trained immunity
Accés en línia:	https://doi.org/10.1002/advs.202509022
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