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Pulmonary Resistance Modification under treatment with Sacubitril/valsartan in Patients with Heart Failure with reduced ejection fraction (PRESENT-HF) - Study protocol and rationale for a multicentre randomised controlled trial

Introduction. Heart failure with reduced ejection fraction (HFrEF) remains a major clinical challenge, partly due to suboptimal implementation of guideline-directed medical therapy and complications such as pulmonary hypertension (PH) that worsen symptoms and prognosis. Material and methods. PRES...

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Principais autores: Ewa Straburzyńska-Migaj, Magdalena Dudek, Jacek Migaj, Agnieszka Bartczak-Rutkowska, Jarosław Hiczkiewicz, Piotr Cygański, Agnieszka Tycińska, Marek Gierlotka, Ewa Kozielska-Nowalany, Jacek Kubica, Małgorzata Tomaszewska, Piotr Sawiński, Lech Paluszkiewicz, Maciej Lesiak, Marta Kałużna-Oleksy
Formato: Artigo
Idioma:Inglês
Publicado em: Poznan University of Medical Sciences 2025-12-01
coleção:Journal of Medical Science
Assuntos:
HFrEF
ARNI
sacubitril/valsartan
pulmonary hypertension
pulmonary hypertension due to left heart disease
Acesso em linha:https://jms.ump.edu.pl/index.php/JMS/article/view/1332
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