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Regulatory T cells in bullous pemphigoid: biological characteristics, dysfunction, and pathogenic roles

Bullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. Its pathogenesis involves the disruption of the basement membrane zone (BMZ), driven by pathogenic autoantibodies and a pronounced inflammatory response. Current first-line therapies, primarily based...

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Tallennettuna:
Päätekijät: Zhimin Wang, Yu Lu, Huan Cui, Yiwen Zhang, Lingzhi Meng, Wenyu Chang, Xuesong Yang, Jianzhou Ye
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2026-04-01
Sarja:Frontiers in Immunology
Aiheet:
bullous pemphigoid
Foxp3
immune tolerance
immunology
regulatory T cells
Linkit:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1775932/full
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