Neuroprotective effects of telmisartan in a harmaline-induced model of essential tremor: modulation of the renin-angiotensin system and inflammatory pathways

BackgroundEssential tremor (ET) is a widespread neurological disorder with mild cerebellar degeneration that affects motor coordination, causing involuntary, rhythmic tremors during action. Excessive brain renin-angiotensin system activation favors pro-inflammatory milieu that is associated with neu...

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Autores principales:	Sama M. Farrag, Amr M. Emam, Ahmed S. Kamel, Muhammed A. Saad, Mona A. Kortam, Noha H. Sayed, Nevine Fathy
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-05-01
Colección:	Frontiers in Pharmacology
Materias:	angiotensin receptors AT1 and AT2 receptors bergmann cells essential tremor inflammatory cytokines mas receptor
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1810499/full
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