Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice

Abstract Depression is one of the most prevalent neuropsychiatric disorders worldwide, and multiple studies have implicated metabolic dysfunction in its pathophysiology. However, the molecular mechanisms by which metabolic pathways modulate depressive‑like behavior remain largely uncharacterized. He...

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Bibliografiske detaljer

Principais autores:	Wanting Dong, Duo Liu, Songsen Fu, Jiaming Zhang, Xi Chen, Songqiang Huang
Format:	Artigo
Sprog:	Inglês
Udgivet:	Wiley 2026-01-01
Serier:	Advanced Science
Fag:	CDGSH iron sulfur domain 1 depression medial prefrontal cortex microglial inflammatory activation pioglitazone
Online adgang:	https://doi.org/10.1002/advs.202508957
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