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Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast

ABSTRACT Inositol pyrophosphate (IPP) dynamics govern expression of the fission yeast phosphate homeostasis regulon via their effects on lncRNA-mediated transcription interference. The growth defects (ranging from sickness to lethality) elicited by fission yeast mutations that inactivate IPP pyropho...

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Hlavní autoři: Beate Schwer, Angad Garg, Ana M. Sanchez, Mindy A. Bernstein, Bradley Benjamin, Stewart Shuman
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2022-02-01
Edice:mBio
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On-line přístup:https://journals.asm.org/doi/10.1128/mbio.03476-21
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