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Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing

The use of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 has moved from bench to bedside in less than 10years, realising the vision of correcting disease through genome editing. The accuracy and safety of this approach relies on the precise control of DNA damage and repair...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Mathilde Meyenberg, Joana Ferreira da Silva, Joanna I. Loizou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-09-01
Schriftenreihe:Frontiers in Genetics
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fgene.2021.728520/full
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