Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing

The use of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 has moved from bench to bedside in less than 10years, realising the vision of correcting disease through genome editing. The accuracy and safety of this approach relies on the precise control of DNA damage and repair...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Mathilde Meyenberg, Joana Ferreira da Silva, Joanna I. Loizou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-09-01
Edice:	Frontiers in Genetics
Témata:	CRISPR-Cas9 genome editing DNA double-strand break homology directed repair non-homologous end-joining microhomology mediated end-joining
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fgene.2021.728520/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!