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Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology

Abstract Background Cerebral organoids (COs) are the most advanced in vitro models that resemble the human brain. The use of COs as a model for Alzheimer’s disease (AD), as well as other brain diseases, has recently gained attention. This study aimed to develop a human AD CO model using normal human...

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Autors principals: Mu Seog Choe, Han Cheol Yeo, Joong Sun Kim, Jean Lee, Hae Jun Lee, Hyung-Ryong Kim, Kyung Min Baek, Na-Yeon Jung, Murim Choi, Min Young Lee
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-04-01
Col·lecció:Stem Cell Research & Therapy
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Accés en línia:https://doi.org/10.1186/s13287-024-03732-1
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