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Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether–lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania: a randomized controlled trial

Abstract Background Artemisinin-based combination therapy (ACT) resistant Plasmodium falciparum represents an increasing threat to Africa. Extended ACT regimens from standard 3 to 6 days may represent a means to prevent its development and potential spread in Africa. Methods Standard 3-day treatment...

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Principais autores: Lwidiko E. Mhamilawa, Billy Ngasala, Ulrika Morris, Eliford Ngaimisi Kitabi, Rory Barnes, Aung Paing Soe, Bruno P. Mmbando, Anders Björkman, Andreas Mårtensson
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-06-01
Serier:Malaria Journal
Fag:
Malaria
Plasmodium falciparum
Artemether–lumefantrine
Drug resistance
Tanzania
Online adgang:http://link.springer.com/article/10.1186/s12936-020-03287-5
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