SLC31A1 exon 1 methylation reduces intracellular copper ion and promotes diabetic cardiac fibrosis

Abstract Background Metal homeostasis is linked to cellular organelles modification. Dynamic lipid droplet (LD)-mitochondria interactions contribute to diabetes-related complications. However, little is known about whether and how copper regulates LD-mitochondria contacts in diabetic cardiac fibrosi...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Kai Song, Hao-Ran Geng, Zhen-Yu Liu, Li-Chan Lin, Bin Tu, He Sun, Sui Mao, Peng Liu, Xin Sun, Yan Shi, Hai-Yang Xuan, Jing-Jing Yang, Jian-Yuan Zhao, Hui Tao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-03-01
Schriftenreihe:	Cardiovascular Diabetology
Schlagworte:	Exon 1 methylation Lipid droplet Mitochondria Copper Diabetic cardiac fibrosis
Online-Zugang:	https://doi.org/10.1186/s12933-026-03124-0
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