Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells

CPT-11 is a first-line chemotherapeutic agent for the treatment of colorectal cancer in clinic. Previous studies including ours have demonstrated that CPT-11 is, however, toxic to the intestinal epithelium and resident peritoneal macrophages. By interacting with B1 cells, the resident peritoneal mac...

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Detalles Bibliográficos

Principais autores:	Wen-Jing Bai, Chen-Guang Li, Cheng-Cheng Zhang, Li-Hui Xu, Qiong-Zhen Zeng, Bo Hu, Zhou Hong, Xian-Hui He, Dong-Yun Ouyang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2018-01-01
Series:	Frontiers in Immunology
Assuntos:	CPT-11 resident peritoneal macrophages peritoneal B1 cells cytotoxicity adoptive transfer
Acceso en liña:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01919/full
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