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Decreased Fc fucosylation aligns with enhanced RSV-specific antibody functionality in adults compared to young children

Abstract Background Respiratory syncytial virus (RSV) is a major cause of severe respiratory tract infections in infants and older adults. While RSV vaccines have recently been approved for older adults and pregnant women, and newborns can be protected through monoclonal antibody immunization, vacci...

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Principais autores: Anke J. Lakerveld, Wenjun Wang, Rutger M. Schepp, Jan Nouta, Steinar Gijze, Anne T. Gelderloos, Nynke Y. Rots, Robert S. van Binnendijk, Gestur Vidarsson, Manfred Wuhrer, Puck B. van Kasteren
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-11-01
Colecção:Communications Medicine
Acesso em linha:https://doi.org/10.1038/s43856-025-01262-2
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