Influence of storage conditions on the toxicity of whole-cell pertussis vaccine in outbred mice

INTRODUCTION. Although whole-cell pertussis vaccine (WCPV) is highly effective, its widespread use is limited by adverse reactions (increased body temperature, administration site oedema, allergic reactions, and febrile seizures). Therefore, there is a need to explore strategies for reducing the tox...

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Principais autores:	I. A. Alekseeva, D. N. Lepikhova, O. Yu. Borisova, A. S. Pimenova, I. Yu. Andrievskaya, I. V. Ibragimkhalilova
Format:	Artigo
Jezik:	Russo
Izdano:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2025-04-01
Serija:	Биопрепараты: Профилактика, диагностика, лечение
Teme:	цельноклеточная коклюшная вакцина цкв специфическая безопасность остаточная токсичность акдс-вакцина коклюшный токсин липоолигосахарид <i>bordetella pertussis</i> условия хранения вакцины инактивация коклюшного токсина
Online dostop:	https://www.biopreparations.ru/jour/article/view/629
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