Absolute quantification of cohesin, CTCF and their regulators in human cells

The organisation of mammalian genomes into loops and topologically associating domains (TADs) contributes to chromatin structure, gene expression and recombination. TADs and many loops are formed by cohesin and positioned by CTCF. In proliferating cells, cohesin also mediates sister chromatid cohesi...

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Autors principals:	Johann Holzmann, Antonio Z Politi, Kota Nagasaka, Merle Hantsche-Grininger, Nike Walther, Birgit Koch, Johannes Fuchs, Gerhard Dürnberger, Wen Tang, Rene Ladurner, Roman R Stocsits, Georg A Busslinger, Béla Novák, Karl Mechtler, Iain Finley Davidson, Jan Ellenberg, Jan-Michael Peters
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2019-06-01
Col·lecció:	eLife
Matèries:	cohesin CTCF genome organization sister chromatid cohesion mass spectrometry fluorescence-correlation spectroscopy
Accés en línia:	https://elifesciences.org/articles/46269
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