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Identification of Novel Inhibitor of Enoyl-Acyl Carrier Protein Reductase (InhA) Enzyme in <i>Mycobacterium tuberculosis</i> from Plant-Derived Metabolites: An In Silico Study

<i>Mycobacterium tuberculosis</i> (<i>M.tb</i>.) enoyl-acyl carrier protein (ACP) reductase (InhA) is validated as a useful target for tuberculosis therapy and is considered an attractive enzyme to drug discovery. This study aimed to identify the novel inhibitor of the InhA enzyme, a potential targe...

Täydet tiedot

Tallennettuna:
Päätekijät: Kratika Singh, Niharika Pandey, Firoz Ahmad, Tarun Kumar Upadhyay, Mohammad Hayatul Islam, Nawaf Alshammari, Mohd Saeed, Lamya Ahmed Al-Keridis, Rolee Sharma
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2022-08-01
Sarja:Antibiotics
Aiheet:
FAS-II
gravacridonediol
InhA
molecular docking
Rutaceae family
tuberculosis
Linkit:https://www.mdpi.com/2079-6382/11/8/1038
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