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Inhibition of LINK-A lncRNA overcomes ibrutinib resistance in mantle cell lymphoma by regulating Akt/Bcl2 pathway

Ibrutinib, a bruton tyrosine kinase (BTK) inhibitor which suppresses B-cell receptor signaling, has remarkably improved the outcome of patients with mantle cell lymphoma (MCL). However, approximately 33% of MCL patients have primary Ibrutinib resistance, and acquired Ibrutinib resistance is nearly u...

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Bibliografiske detaljer
Principais autores: Ye Zhang, Peng Lu, Yan Zhou, Lifei Zhang
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2021-12-01
Serier:PeerJ
Fag:
Online adgang:https://peerj.com/articles/12571.pdf
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