Ebola-GP DNA Prime rAd5-GP Boost: Influence of Prime Frequency and Prime/Boost Time Interval on the Immune Response in Non-human Primates

Heterologous prime-boost immunization regimens are a common strategy for many vaccines. DNA prime rAd5-GP boost immunization has been demonstrated to protect non-human primates against a lethal challenge of Ebola virus, a pathogen that causes fatal hemorrhagic disease in humans. This protection corr...

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Autores principales:	Hadar Marcus, Emily Thompson, Yan Zhou, Michael Bailey, Mitzi M. Donaldson, Daphne A. Stanley, Clement Asiedu, Kathryn E. Foulds, Mario Roederer, Juan I. Moliva, Nancy J. Sullivan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2021-03-01
Colección:	Frontiers in Immunology
Materias:	vaccine Ebola prime boost CD8+ CD4+
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.627688/full
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