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The dynamics of stress p53-Mdm2 network regulated by p300 and HDAC1.

We construct a stress p53-Mdm2-p300-HDAC1 regulatory network that is activated and stabilised by two regulatory proteins, p300 and HDAC1. Different activation levels of [Formula: see text] observed due to these regulators during stress condition have been investigated using a deterministic as well a...

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Principais autores: Akshit Arora, Saurav Gera, Tanuj Maheshwari, Dhwani Raghav, Md Jahoor Alam, R K Brojen Singh, Subhash M Agarwal
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2013-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC3577848?pdf=render
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