Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag--implications for research into amyotrophic lateral sclerosis (ALS).

<h4>Background</h4>Since the discovery that mutations in the enzyme SOD1 are causative in human amyotrophic lateral sclerosis (ALS), many strategies have been employed to elucidate the toxic properties of this ubiquitously expressed mutant protein, including the generation of GFP-SOD1 chimaeric prot...

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Autores principales:	James C Stevens, Ruth Chia, William T Hendriks, Virginie Bros-Facer, Jan van Minnen, Joanne E Martin, Graham S Jackson, Linda Greensmith, Giampietro Schiavo, Elizabeth M C Fisher
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2010-03-01
Colección:	PLoS ONE
Acceso en línea:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009541&type=printable
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