A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes

The ubiquitin-editing protein A20 (TNFAIP3) is a known key player in the regulation of immune responses in many organs. Genome-wide associated studies (GWASs) have linked A20 with a number of inflammatory and autoimmune disorders, including psoriasis. Here, we identified a previously unrecognized ro...

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Detalhes bibliográficos

Principais autores:	Maria Feoktistova, Roman Makarov, Sihem Brenji, Anne T. Schneider, Guido J. Hooiveld, Tom Luedde, Martin Leverkus, Amir S. Yazdi, Diana Panayotova-Dimitrova
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-02-01
coleção:	Cells
Assuntos:	cell death keratinocytes a20 nf-κb signaling ripoptosome
Acesso em linha:	https://www.mdpi.com/2073-4409/9/2/351
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