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Mucosa-like differentiation of head and neck cancer cells is inducible and drives the epigenetic loss of cell malignancy

Abstract Head and neck squamous cell carcinoma (HNSCC) is a highly malignant disease with high death rates that have remained substantially unaltered for decades. Therefore, new treatment approaches are urgently needed. Human papillomavirus-negative tumors harbor areas of terminally differentiated t...

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I tiakina i:
Ngā kaituhi matua: Felix Oppel, Sarah Gendreizig, Laura Martinez-Ruiz, Javier Florido, Alba López-Rodríguez, Harkiren Pabla, Lakshna Loganathan, Leonie Hose, Philipp Kühnel, Pascal Schmidt, Matthias Schürmann, Judith Martha Neumann, Flavian Viyof Ful, Lars Uwe Scholtz, Dina Ligum, Frank Brasch, Karsten Niehaus, Germaine Escames, Tobias Busche, Jörn Kalinowski, Peter Goon, Holger Sudhoff
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Publishing Group 2024-10-01
Rangatū:Cell Death and Disease
Urunga tuihono:https://doi.org/10.1038/s41419-024-07065-y
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