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Hepatitis B virus induces sorafenib resistance in liver cancer via upregulation of cIAP2 expression

Abstract Background HBV promotes cell survival by upregulating the expression of the cellular inhibitor of apoptosis protein 2 (cIAP2), however whether it is involved in HBV-induced sorafenib resistance in liver cancer remains unclear. Methods cIAP2 overexpression and knockdown was adopted to assess...

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Principais autores: Shouhua Zhang, Nuoya Li, Yanling Sheng, Wen Chen, Qiangliang Ma, Xin Yu, Jianping Lian, Junquan Zeng, Yipeng Yang, Jinlong Yan
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2021-03-01
Series:Infectious Agents and Cancer
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Acceso en liña:https://doi.org/10.1186/s13027-021-00359-2
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