Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity
Citrate synthase (CS) is a key mitochondrial enzyme. The aim of this study was to test the hypothesis that low CS activity impairs the metabolic health of mice fed a high fat diet (HFD) and promotes palmitate-induced lipotoxicity in muscle cells. C57BL/6J (B6) mice and congenic B6.A-(rs3676616-D10Ut...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2019-01-01
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| coleção: | Journal of Nutrition and Metabolism |
| Acesso em linha: | http://dx.doi.org/10.1155/2019/8594825 |
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