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Polo-like kinase 1 promotes pulmonary hypertension

Abstract Background Pulmonary hypertension (PH) is a lethal vascular disease with limited therapeutic options. The mechanistic connections between alveolar hypoxia and PH are not well understood. The aim of this study was to investigate the role of mitotic regulator Polo-like kinase 1 (PLK1) in PH d...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Rongrong Chen, Hongfei Wang, Cuiting Zheng, Xiyu Zhang, Li Li, Shengwei Wang, Hongyu Chen, Jing Duan, Xian Zhou, Haiyong Peng, Jing Guo, Anchen Zhang, Feifei Li, Wang Wang, Yu Zhang, Jun Wang, Chen Wang, Yan Meng, Xinling Du, Hongbing Zhang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2023-08-01
Seri Bilgileri:Respiratory Research
Konular:
Pulmonary hypertension
Hypoxia
Polo-like kinase 1
HIF1α
RELA/p65
Online Erişim:https://doi.org/10.1186/s12931-023-02498-z
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