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Formulation, Preparation, Characterization, and Evaluation of Dicarboxylic Ionic Liquid Donepezil Transdermal Patches

Donepezil (DPZ) is generally administered orally to treat Alzheimer’s disease (AD). However, oral administration can cause gastrointestinal side effects. Therefore, to enhance compliance, a new way to deliver DPZ from transdermal patch was developed. Ionic bonds were created by dissolving dicarboxyl...

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Principais autores: Linh Dinh, Soohun Lee, Sharif Md Abuzar, Heejun Park, Sung-Joo Hwang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-01-01
Serier:Pharmaceutics
Fag:
donepezil
Alzheimer’s disease
dicarboxylic acid
ionic liquid
transdermal drug delivery
transdermal patch
Online adgang:https://www.mdpi.com/1999-4923/14/1/205
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