Potential glutamatergic and GABAergic false neurotransmitters in models of excitation-inhibition imbalance

Abstract We previously determined that 2-Methylglutamate (2MeGlu) and 4-aminopentanoic acid (4APA) have neurochemical properties of glutamatergic and GABAergic false neurotransmitters (FNTs); here, we tested whether their activity impacts mouse models with excitation-inhibition (E-I) imbalance. We f...

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Auteurs principaux:	Amalia Perna, Jing Zhao, Chandresh R. Gajera, Marcus Schonemann, Nay L. Saw, Mehrdad Shamloo, Kathleen S. Montine, Albert W. Garofalo, Thomas J. Montine
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2026-05-01
Collection:	Scientific Reports
Accès en ligne:	https://doi.org/10.1038/s41598-026-54218-4
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